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{"type":"standard","title":"Lipophilic efficiency","displaytitle":"Lipophilic efficiency","namespace":{"id":0,"text":""},"wikibase_item":"Q17064984","titles":{"canonical":"Lipophilic_efficiency","normalized":"Lipophilic efficiency","display":"Lipophilic efficiency"},"pageid":28819446,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/c/c8/LiPE_Plot.png/330px-LiPE_Plot.png","width":320,"height":346},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/c/c8/LiPE_Plot.png","width":648,"height":700},"lang":"en","dir":"ltr","revision":"1170235888","tid":"d06b020d-3a23-11ee-be5c-dfd86ba9763c","timestamp":"2023-08-13T21:53:19Z","description":"Parameter used in drug design","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Lipophilic_efficiency","revisions":"https://en.wikipedia.org/wiki/Lipophilic_efficiency?action=history","edit":"https://en.wikipedia.org/wiki/Lipophilic_efficiency?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Lipophilic_efficiency"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Lipophilic_efficiency","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Lipophilic_efficiency","edit":"https://en.m.wikipedia.org/wiki/Lipophilic_efficiency?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Lipophilic_efficiency"}},"extract":"Lipophilic efficiency (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. For a given compound LiPE is defined as the pIC50 (or pEC50) of interest minus the LogP of the compound.","extract_html":"
Lipophilic efficiency (LiPE), sometimes referred to as ligand-lipophilicity efficiency (LLE) is a parameter used in drug design and drug discovery to evaluate the quality of research compounds, linking potency and lipophilicity in an attempt to estimate druglikeness. For a given compound LiPE is defined as the pIC50 (or pEC50) of interest minus the LogP of the compound.
"}{"slip": { "id": 155, "advice": "What could you increase? What could you reduce?"}}
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{"fact":"Cats walk on their toes.","length":24}
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